Spray in bedliner, so I sweep out the big stuff, spray it down and let it dry. If there is any caked on mud etc. I'll brush it clean. I do VRT the part that goes over the bedrails, the rest is not visible to most people unless the tailgate is down.
My 67 on the other hand, likely won't get a spray in, so it will probably be washed/waxed/detailed, especially since it will be lower to the ground and visible, probably just keep a rubber mat in the bed when I need to haul something.