i run spacers all around no loctite, just torque to like 100 or 110 ft lbs iirc, been on there for 2 years. i only check them when i swap from summer to winter wheels and vise versa
i have towed my racecar in a 20ft enclosed trailer full of shit, i have also towed a bunch of cars on an open trailer. the larger tires suck for pulling but the spacers have nothing to do with that